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Dried blood spots (DBS)

The technique of gathering whole blood samples on paper, termed as Dried Blood Spot (DBS), has a rich history tracing back to the early 1960s. It was initially introduced in newborn screening programs for the detection of inherited metabolic disorders. Today, this modern, forward-thinking approach revolutionizes blood sampling, accommodating the needs of the future.

Dried-blood-spots-rev-JPEG.jpg – Vitas Analytical Services


DBS (Dried Blood Spot) collection is quickly gaining recognition for its numerous benefits over traditional blood sampling methods. It's cost-effective, less invasive, and simplifies both collection and transportation, reducing infection risk. Furthermore, it needs only a few drops of blood, making it an increasingly essential platform for quantitative biomarker analysis.

Key advantages of DBS collection include:

  • Flexibility of sample collection, allowing for remote locations like homes, schools, and field sites

  • Elimination of the need for medical professionals as no venipuncture is required

  • Minimal invasiveness

  • Requirement of a small blood volume

  • Convenient transportation at room temperature via regular mail

  • Prolonged stability

Vitas provides a variety of DBS collection kits to suit different needs. Single kits can be shipped directly to individual locations, and we also cater to larger studies, with kit quantities ranging from 100 to 100,000. Contact us to identify the optimal choice for your requirements.

We have the capability to develop assays for a wide range of biomarkers based on demand. The extent of assay validation is agreed upon with the sponsor. We provide various reporting options, with typical biomarkers including:

  • Fatty acids

  • Amino acids

  • Vitamins

  • Lipids like: Cholesterol, triglycerides

  • Carotenoids

  • Inflammatory markers

  • Comprehensive lipidomics by TOF-MS (several hundred different lipids)

  • Proteins like: C-peptide, glucose, CRP, IGF-1, PYY, HbA1c, etc.

See our DBS instruction video to obtain optimal sample quality

Applications

Number Method
AM-574 Quantification of NT-proBNP in human DBS
AM-555 Quantification of Methylmalonic acid (MMA) in dried blood spots (DBS) and plasma/serum using GC-MS
AM-543 Quantification of Methylmalonic acid (MMA) in DBS using LC-MS/MS
AM-536 Quantification of gallic acid, syringic acid and protocatechuic acid in plasma, blood and DBS by LC-MS/MS
AM-523 Quantification of short chain fatty acids (SCFA) in plasma, serum, blood, urine, DBS and feces using LC-MS/MS
AM-514 Quantification of Vitamin D (Vit-D3 and Vit-D2) and Menaquinone-7 (MK-7) in DBS using LC-MSMS
AM-511 Quantification of Vitamin D (Vit-D3 and Vit-D2) and Vitamin A (Retinol) in DBS using LC-MSMS
AM-508 Metal analysis in mitra stick or DBS samples with LC-ICP-MS
AM-496 Quantiative fatty acid analysis in dried blood spots (DBS), whole blood from mice using GC-FID
AM-495-A Detection of SARS-CoV-2 (COVID-19) antibodies in dried blood spots (DBS)
AM-472 Quantification of 8isoPGF2a in DBS using HPLC-MSMS
AM-451 Fatty acid profile in dried bloos spots (DBS) using GC-FID
AM-443 Quantification of mature BDNF in DBS using ELISA
AM-438 Quantification of hs-CRP in sticks, DBS, whole blood and plasma using MSD
AM-434 Quantification of steroids (cortisone, cortisol, testosterone and 25-OH vitamin D3) in dried blood spots and plasma using LC-MS/MS.
AM-430 Quantification of Menaquinone-7 (MK-7) in DBS by LC-MS/MS
AM-426 Quantification of C-peptide in human serum from ADX100 card using ELISA
AM-425 Quantification of Glucose in human blood from ADX cards using modified GPO/DAOS method
AM-424 Quantification of total Cholesterol in human blood from ADX cards using modified CO/DAOS method
AM-406-DBS-01 Comprehensive lipidomics analysis of dried blood spots (DBS)
AM-399 Quantification of hs-CRP in Mitra stix using CUBE POC instrument
AM-397 Determination of 25-OH vit D from Dried Blood Spots by LC-MS/MS
AM-395 Determination of 25-OH vit D from Dried Blood Spots by ELISA kit
AM-392 Quantification of HDL in whole blood from Mitra sticks using ELISA
AM-391 Quantification of HDL in whole blood from Mitra sticks
AM-389 Quantification of cholesterol in whole blood from dried blood spots (DBS) by HPLC-UV
AM-373 Quantification of 16 amino acids in Dried Blood Sticks and Dried Blood Spots
AM-371 Quantification of Hemoglobin in Dried Blood Spots using colorimetric assay kit
AM-367 Quantification of HbA1c in Mitra stick using Cube POC instrument
AM-339 Simultaneous quantification of carotenoids, vitamin A and vitamin E in dried blood spots (DBS)
AM-318 Quantification of C-peptide in DBS/Mitra stick using ELISA
AM-305 Quantification of amino acids in dried blood spots (DBS) using GC-MS
AM-296 Quantification of adiponectin in dried blood spots (DBS) using ELISA
AM-289 Quantification of cholesterol in dried blood spots (DBS )using GC-FID
AM-265 Quantification of lipoprotein A (Apo A) in dried blood spots (DBS) using ELISA
AM-263 Quantification of leptin in dried blood spots (DBS) using ELISA
AM-250 Quantification of triglycerides in dried blood spots (DBS) using ELISA
AM-248 Quantitation of IGF-1 in dried blood spots (DBS) using ELISA
AM-157 Fatty acid profile in dried blood spots (DBS) using GC-FID
AM-156 Quantification of vitamin K1 in dried blood spots (DBS) by LC-FLD
AM-155 Quantification of vitamin E in dried blood spots (DBS) by LC-FLD
AM-145 Quantification of retinol in dried blood spots (DBS) from humans by LC-MS
AM-127 Quantification of carotenoids in dried blood spots (DBS) by LC-UV
AM-113 Quantification of caffeine and paraxanthin in dried blood spots (DBS) using LC-UV
AM-099 Fatty acid profile in dried blood spots (DBS) from mice using GC-FID
AM-094 Quantification of transferrin receptor (TfR) in dried blood spots by EIA
AM-068 Quantification of vitamin A in dried blood spots (DBS) using LC/MS with APCI detection
AM-038 Carotenoids in dried blood spot (DBS) by HPLC-UV
AM-037 Quantification of 25-hydroxy vitamin D3 in dried blood spots (DBS) by HPLC-MS/MS
AM-036 Quantification of glucose in dried blood spots (DBS) by derivatisation and spectrophotometry
AM-035 Quantification of total cholesterol in dried blood spots (DBS) by HPLC-UV
AM-009 Omega3-Index in dried blood spots (DBS)
View complete list of applications