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Chemical Analysis

Dried blood spot (DBS) sample collection for determination of the oxidative stress biomarker 8-epi-PGF(2α) in humans using liquid chromatography/tandem mass spectrometry

Bastani NE, Gundersen TE, Blomhoff R.

Rapid Commun Mass Spectrom. 2012 Mar 30;26(6):645-52.


Determining vitamin D status: a comparison between commercially available assays.

Snellman G, Melhus H, Gedeborg R, Byberg L, Berglund L, Wernroth L, Michaëlsson K.

PLoS One. 2010 Jul 13;5(7):e11555.


Holmøy T, Moen SM, Gundersen TE, Holick MF, Fainardi E, Castellazzi M, Casetta I.

25-hydroxyvitamin D in cerebrospinal fluid during relapse and remission of multiple sclerosis.

Mult Scler. 2009 Nov;15(11):1280-5. Epub 2009 Oct 6.


Vitamin D status among immigrant mothers from Pakistan, Turkey and Somalia and their infants attending child health clinics in Norway.

Madar AA, Stene LC, Meyer HE.

Br J Nutr. 2009 Apr;101(7):1052-8. Epub 2008 Sep 9.


Effect of free vitamin D(2) drops on serum 25-hydroxyvitamin D in infants with immigrant origin: a cluster randomized controlled trial.

Madar AA, Klepp KI, Meyer HE.

Eur J Clin Nutr. 2009 Apr;63(4):478-84. Epub 2008 Jan 30


A randomised comparison of increase in serum 25-hydroxyvitamin D concentration after 4 weeks of daily oral intake of 10 microg cholecalciferol from multivitamin tablets or fish oil capsules in healthy young adults.

Holvik K, Madar AA, Meyer HE, Lofthus CM, Stene LC.

Br J Nutr. 2007 Sep;98(3):620-5. Epub 2007 Apr 24


Håkan Melhus*, Greta Snellman, Rolf Gedeborg, Liisa Byberg, Lars Berglund, Hans Mallmin, Per Hellman, Rune Blomhoff, Emil Hagström, Johan Ärnlöv, and Karl Michaëlsson

Plasma 25-Hydroxyvitamin D Levels and Fracture Risk in a Community-Based Cohort of Elderly Men in Sweden

Journal of Clinical Endocrinology & Metabolism , doi:10.1210/jc.2009-2699


Snellman G, Melhus H, Gedeborg R, Olofsson S, Wolk A, et al. (2009)Seasonal Genetic Influence on Serum 25-Hydroxyvitamin D Levels: A Twin Study.

PLoS ONE 4(11): e7747. doi:10.1371/journal.pone.0007747


Bastani NE, Gundersen TE, Blomhoff R.

Determination of 8-epi PGF(2alpha) concentrations as a biomarker of oxidative stress using triple-stage liquid chromatography/tandem mass spectrometry.

Rapid Commun Mass Spectrom. 2009 Aug 10;23(18):2885-2890.


Schmidt K, Hughes C, Chudek JA, Goodyear SR, Aspden RM, Talbot R, Gundersen TE, Blomhoff R, Henderson C, Wolf CR, Tickle C.

Cholesterol metabolism: the main pathway acting downstream of cytochrome P450 oxidoreductase in skeletal development of the limb.

Mol Cell Biol. 2009 May;29(10):2716-29. Epub 2009 Mar 9.


Ström K, Gundersen TE, Hansson O, Lucas S, Fernandez C, Blomhoff R, Holm C. 
Hormone-sensitive lipase (HSL) is also a retinyl ester hydrolase: evidence from mice lacking HSL.

FASEB J. 2009 Jul;23(7):2307-16. Epub 2009 Feb 26.


Noble BR, Babiuk RP, Clugston RD, Underhill TM, Sun H, Kawaguchi R, Walfish PG, Blomhoff R, Gundersen TE, Greer JJ.
Mechanisms of action of the congenital diaphragmatic hernia-inducing teratogen nitrofen. . Am J Physiol Lung Cell Mol Physiol. 2007 Oct;293(4):L1079-87.


Berhe N, Halvorsen BL, Gundersen TE, Myrvang B, Gundersen SG, Blomhoff R. 
Reduced serum concentrations of retinol and alpha-tocopherol and high concentrations of hydroperoxides are associated with community levels of S. mansoni infection and schistosomal periportal fibrosis in Ethiopian school children. Am J Trop Med Hyg. 2007 May;76(5):943-9.


Gundersen TE, Bastani NE, Blomhoff R. 
Quantitative high-throughput determination of endogenous retinoids in human plasma using triple-stage liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom. 2007;21(7):1176-86.


Sakhi AK, Blomhoff R, Gundersen TE. 
Simultaneous and trace determination of reduced and oxidized glutathione in minute plasma samples using dual mode fluorescence detection and column switching high performance liquid chromatography. J Chromatogr A. 2007 Feb 23;1142(2):178-84.

Karlsen A, Blomhoff R, Gundersen TE. 
Stability of whole blood and plasma ascorbic acid. Eur J Clin Nutr. 2007 Feb 7.


Brantsaeter ALHaugen MRasmussen SEAlexander JSamuelsen SOMeltzer HM.

Urine flavonoids and plasma carotenoids in the validation of fruit, vegetable and tea intake during pregnancy in the Norwegian Mother and Child Cohort Study (MoBa).

Public Health Nutr. 2007 Aug;10(8):838-47. Epub 2007 May 11.


Gundersen TE. 
Methods for detecting and identifying retinoids in tissue. J Neurobiol. 2006 Jun;66(7):631-44. Review.


Sakhi AK, Russnes KM, Smeland S, Blomhoff R, Gundersen TE
Simultaneous quantification of reduced and oxidized glutathione in plasma using a two-dimensional chromatographic system with parallel porous graphitized carbon columns coupled with fluorescence and coulometric electrochemical detection. J Chromatogr A. 2006 Feb 3;1104(1-2):179-89.


Karlsen A, Blomhoff R, Gundersen TE. 
High-throughput analysis of vitamin C in human plasma with the use of HPLC with monolithic column and UV-detection., J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Sep 25;824(1-2):132-8 


Drevon CA, Henriksen HB, Sanderud M, Gundersen TE, Blomhoff R.
Biological effects of vitamin K and concentration of vitamin K in Norwegian food.Tidsskr Nor Laegeforen. 2004 Jun 17;124(12):1650-4. Review.


Otto DM, Henderson CJ, Carrie D, Davey M, Gundersen TE, Blomhoff R, Adams RH, Tickle C, Wolf CR. 
Identification of novel roles of the cytochrome p450 system in early embryogenesis: effects on vasculogenesis and retinoic Acid homeostasis.Mol Cell Biol. 2003 Sep;23(17):6103-16.


Karlsen A, Alexander G, Blomhoff R, Gundersen TE. 
Capillary high-performance liquid chromatographic determination of lutein and zeaxanthin in aqueous humor from a single mouse eye. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Sep 25;795(1):17-23.

Ayala MN, Soderberg PG.
Reversal of reciprocity failure for UVR-induced cataract with vitamin E. Ophthalmic Res. 2005 May-Jun;37(3):150-5.

Hogstrom M, Nordstrom A, Nordstrom P. 
Relationship between vitamin D metabolites and bone mineral density in young males: a cross-sectional and longitudinal study.Calcif Tissue Int. 2006 Aug;79(2):95-101.

Lind PM, Johansson S, Ronn M, Melhus H. 
Subclinical hypervitaminosis A in rat: measurements of bone mineral density (BMD) do not reveal adverse skeletal changes. Chem Biol Interact. 2006 Jan 5;159(1):73-80.


Halvorsen BL, Holte K, Myhrstad MC, Barikmo I, Hvattum E, Remberg SF, Wold AB, Haffner K, Baugerod H, Andersen LF, Moskaug O, Jacobs DR Jr, Blomhoff R. 
A systematic screening of total antioxidants in dietary plants. J Nutr. 2002 Mar;132(3):461-71.


Gundersen TE, Blomhoff R. 
On-line solid-phase extraction and isocratic separation of retinoic acid isomers in microbore column switching system. Methods Enzymol. 1999;299:430-41.


Sakhi AK, Gundersen TE, Ulven SM, Blomhoff R, Lundanes E.
Quantitative determination of endogenous retinoids in mouse embryos by high-performance liquid chromatography with on-line solid-phase extraction, column switching and electrochemical detection. J Chromatogr A. 1998 Dec 18;828(1-2):451-60.


Gundersen TE, Blomhoff R. 
Qualitative and quantitative liquid chromatographic determination of natural retinoids in biological samples. J Chromatogr A. 2001 Nov 23;935(1-2):13-43. Review.


Ulven SM, Gundersen TE, Sakhi AK, Glover JC, Blomhoff R. 
Quantitative axial profiles of retinoic acid in the embryonic mouse spinal cord: 9-cis retinoic acid only detected after all-trans-retinoic acid levels are super-elevated experimentally. Dev Dyn. 2001 Nov;222(3):341-53.


Hoover F, Gundersen TE, Ulven SM, Michaille JJ, Blanchet S, Blomhoff R, Glover JC. 
Quantitative assessment of retinoid signaling pathways in the developing eye and retina of the chicken embryo. J Comp Neurol. 2001 Jul 30;436(3):324-35.


Ulven SM, Gundersen TE, Weedon MS, Landaas VO, Sakhi AK, Fromm SH, Geronimo BA, Moskaug JO, Blomhoff R. 
Identification of endogenous retinoids, enzymes, binding proteins, and receptors during early postimplantation development in mouse: important role of retinal dehydrogenase type 2 in synthesis of all-trans-retinoic acid. Dev Biol. 2000 Apr 15;220(2):379-91.

Christensen EI, Moskaug JO, Vorum H, Jacobsen C, Gundersen TE, Nykjaer A, Blomhoff R, Willnow TE, Moestrup SK. 
Evidence for an essential role of megalin in transepithelial transport of retinol. J Am Soc Nephrol. 1999 Apr;10(4):685-95.

Halvorsen BL, Holte K, Myhrstad MC, Barikmo I, Hvattum E, Remberg SF, Wold AB, Haffner K, Baugerod H, Andersen LF, Moskaug O, Jacobs DR Jr, Blomhoff R.
A systematic screening of total antioxidants in dietary plants. J Nutr. 2002 Mar;132(3):461-71.


Sonesson B, Eide S, Rorsman H, Rosengren E., Seasonal variation of tyrosinase activity in serum.

Acta Derm Venereol 1995 Jul;75(4):283-6